The Prusa is a Reprap DIY style 3D printer that was constructed and improved by several MIT UROPs. Reprap printers are 3D printers made as part of an effort to make a self-replicating machine, and as such, the printer is made using many 3D printed parts (and is a great example of integrated hardware in 3D printed parts). Although the printer looks unfinished, when tuned properly the machine prints pretty well. This machine is an excellent tool to learn about the more advanced details of 3D printing, as the software and hardware both allow for high levels of user control over the 3D printing process.
This style printer only has one material, so if supports are needed, it is printed in the same material as the model. Same-material support can be tricky to remove, as it involved cutting the connections to the model using clippers and can leave behind marks that give the model a poor surface finish. Therefore, it is a good idea to try to minimize usage of support material for these printers. Take a look at a few 3D printing design tips here.